The same, only different

Bacillus cereus Biofilms—Same, Only Different

Bacillus cereus displays a high diversity of lifestyles and ecological niches and include beneficial as well as pathogenic strains. These strains are widespread in the environment, are found on inert as well as on living surfaces and contaminate persistently the production lines of the food industry. Biofilms are suspected to play a key role in this ubiquitous distribution and in this persisten...

Chiral toxicology: it's the same thing...only different.

Chiral substances possess a unique architecture such that, despite sharing identical molecular formulas, atom-to-atom linkages, and bonding distances, they cannot be superimposed. Thus, in the environment of living systems, where specific structure-activity relationships may be required for effect (e.g., enzymes, receptors, transporters, and DNA), the physiochemical and biochemical properties o...

The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle.

Cell cycle checkpoints activated by DNA double-strand breaks (DSBs) are essential for the maintenance of the genomic integrity of proliferating cells. Following DNA damage, cells must detect the break and either transiently block cell cycle progression, to allow time for repair, or exit the cell cycle. Reversal of a DNA-damage-induced checkpoint not only requires the repair of these lesions, bu...

The Same, Only Different: Threat Management Systems as Homologues in the Tree of Life

The same, but different

The Dutch healthcare sector has seen many major changes lately: the introduction of a new health insurance scheme, a shift from supply-based healthcare to a demand-based system and a trend towards increasingly assertive patients. This requires a new approach to the education and training of future doctors. How is this approach implemented in practice and how do the changes affect medical studen...